IntroductionAt present, in the UK, live lobe donation of the lung is generally considered in the context of patients with cystic fibrosis which is a life-threatening, inherited disease.1 However, if this technique is successfully developed it may be applicable to other patients with end stage lung disease. Cystic fibrosis is a disease where the major morbidity and mortality is due to pulmonary infection and respiratory failure.2 In l938 70% of patients born with CF died within one year of birth, but (...) now the average survival has improved to 32 years.1 The improved survival has been due to improved medical care, but also, and in very large measure, to the devotion of the families who have carried out time-consuming daily treatments such as chest physiotherapy, nebuliser treatment, high calorie diets etc. To these patients and their families lung transplantation brought new hope.3 The first successful transplant for CF was performed in the UK in 1985 and we now have patients alive and well more than ten years after transplantation. However, sadly, nearly 50% of patients with CF die on the transplant waiting list because of a shortage of donor organs from brain stem dead donors. This is a tragedy for the individual patient, the families and those who care for them. Is there a way forward?Can the number of organs available for transplantation be increased?Education of the public so that a relative of a brain dead individual will give permission for the organs to be used has been carried out for many years but only with a small increase in the number of available organs. “Required request” where doctors would be required, by law, to ask relatives of brain dead patients to consider transplantation and “assume consent” where consent to donation is assumed unless there is evidence to the contrary, do not have the …. (shrink)

At present, in the UK, live lobe donation of the lung is generally considered in the context of patients with cystic fibrosis (CF) which is a life-threatening, inherited disease.1 However, if this technique is successfully developed it may be applicable to other patients with end stage lung disease. Cystic fibrosis is a disease where the major morbidity and mortality is due to pulmonary infection and respiratory failure.2 In l938 70% of patients born with CF died within one year of birth, (...) but now the average survival has improved to 32 years.1 The improved survival has been due to improved medical care, but also, and in very large measure, to the devotion of the families who have carried out time-consuming daily treatments such as chest physiotherapy, nebuliser treatment, high calorie diets etc. To these patients and their families lung transplantation brought new hope.3 The first successful transplant for CF was performed in the UK in 1985 and we now have patients alive and well more than ten years after transplantation. However, sadly, nearly 50% of patients with CF die on the transplant waiting list because of a shortage of donor organs from brain stem dead donors. This is a tragedy for the individual patient, the families and those who care for them. Is there a way forward? Education of the public so that a relative of a brain dead individual will give permission for the organs to be used has been carried out for many years but only with a small increase in the number of available organs. “Required request” where doctors would be required, by law, to ask relatives of brain dead patients to consider transplantation and “assume consent” where consent to donation is assumed unless there is evidence to the contrary, do not have the …. (shrink)

Institutional investors are increasingly becoming active owners through voting their shares and engaging in dialogue with investee companies to improve corporate environmental, social and corporate governance (ESG) performance. This article applies a model of stakeholder salience to the shareholder context, analysing the attributes of power, legitimacy and urgency, to determine the factors that are likely to enhance shareholder salience. It is found that a strong business case and the values of the managers of investee companies are likely to be the (...) most important contributors to shareholder salience. (shrink)

In this paper we study three-valued simple games as a natural extension of simple games. We analyze to which extent well-known results on the core and the Shapley value for simple games can be extended to this new setting. To describe the core of a three-valued simple game we introduce vital players, in analogy to veto players for simple games. Moreover, it is seen that the transfer property of Dubey can still be used to characterize the Shapley value for three-valued (...) simple games. We illustrate three-valued simple games and the corresponding Shapley value in a parliamentary bicameral system. (shrink)

Provability, Computability and Reflection.

Many philosophers maintain that works of art, in particular films and novels, cannot function as thought experiments. Most who claim this make their case by setting the bar for what can count as a philosophical thought experiment very high. It is argued here not that these positions are necessarily mistaken, but that there is a large gray area that is seldom acknowledged between what counts as a philosophical thought experiment narrowly defined and what counts as “being used to illustrate a (...) philosophical point,” where the fiction is imported into an already complete external argument. I contend that these are not the only alternatives available, that intuition pumps and variant case arguments provide better grounds for comparison than has been acknowledged, and that there are uses to which filmic illustrations in particular may be put that make distinctive and cognitive contributions of their own. In the course of making this case, it is stressed both that emotional response has clearly cognitive aspects and that many thought experiments with lower stakes rely on eliciting emotional response. (shrink)

In this paper, logics are conceived as two-sorted first-order structures, and we argue that this broad definition encompasses a wide class of logics with theoretical interest as well as interest from the point of view of applications. The language, concepts and methods of model theory can thus be used to describe the relationship between logics through morphisms of structures called transfers. This leads to a formal framework for studying several properties of abstract logics and their attributes such as consequence operator, (...) syntactical structure, and internal transformations. In particular, we treat Belief Revision Systems (BRS) as our main example, defining the Wide Belief Revision Systems (WBRS''s). This generalization allows us to define BRS''s in an abstract setting for classical and non-standard logics. We also show how the concept of translation between logics can be obtained as a particular case of transfers. (shrink)

The same research proposal was submitted to 24 district health authority (DHA) research ethics committees in different parts of the country. The objective was to obtain permission for a multi-centre research project. The study of neonatal care in different types of unit (regional, subregional and district), required that four health authorities were approached in each of six widely separated health regions in England. Data were collected and compared concerning aspects of processing, including application forms, information required, timing and decision-making. The (...) key finding was that ethics committees received and processed the applications variably, reflecting individual factors and local problems. To improve consensus and facilitate multicentre studies, standard forms and instructions are suggested and the establishment of a national committee or advisory group advocated. (shrink)

Synaesthesia is a condition in which one type of stimulation evokes the sensation of another, as when the hearing of a sound produces photisms, i.e. mental percepts of colours. R is a 20 year old colour blind subject who, in addition to the relatively common grapheme-colour synaesthesia, presents a rarely reported cross modal perception in which a variety of visual stimuli elicit aura-like percepts of colour. In R, photisms seem to be closely related to the affective valence of stimuli and (...) typically bring out a consistent pattern of emotional responses. The present case study suggests that colours might be an intrinsic category of the human brain. We developed an empirical methodology that allowed us to study the subject's otherwise inaccessible phenomenological experience. First, we found that R shows a Stroop effect elicited by photisms despite the fact that he does not show a regular Stroop with real colours. Secondly, by manipulating the colour context we confirmed that colours can alter R's emotional evaluation of the stimuli. Furthermore, we demonstrated that R's auras may actually lead to a partially inverted emotional spectrum where certain stimuli bring out emotional reactions opposite to the normal ones. These findings can only be accounted for by considering R's subjective colour experience or qualia. Therefore the present paper defends the view that qualia are a useful scientific concept that can be approached and studied by experimental methods. (shrink)

What kind of feeling is shame? Why are we ashamed and what are the consequences that this emotion has on the subject? Is it a private or a "social" emotion? How many types of shame exist? Is vicarious shame always shameful? What are the ways in which art has represented shame? What are the relations between shame, guilt, embarrassment and censorship? Is it possible to be immune to shame? Would "Not being ashamed" count as a virtue or is it a (...) morally reprehensible attitude? Sensibilia. Colloquium on Perception and Experience investigated the different ways in which shame can be described and staged, presupposed and understood. The proposals and the points of view collected in this volume relate in an original and interdisciplinary way different areas of research all equally interested in reflecting on a complex and stratified feeling. The result was a heated debate on (ancient and contemporary) inconvenient, thorny and "shameful" issues. (shrink)

Context: In the digital era, it is important to investigate the potential impact of digital technologies in education and how such tools can be successfully integrated into the mathematics classroom. Similarly to many others in the constructionism community, we have been inspired by the idea set out originally by Papert of providing students with appropriate “vehicles” for developing “Mathematical Ways of Thinking.” Problem: A crucial issue regarding the design of digital tools as vehicles is that of “transfer” or “bridging” i.e., (...) what mathematical knowledge is transferred from students’ interactions with such tools to other activities such as when they are doing “paper-and-pencil” mathematics, undertaking traditional exam papers or in other formal and informal settings. Method: Through the lens of a framework for algebraic ways of thinking, this article analyses data gathered as part of the MiGen project from studies aiming at investigating ways to build bridges to formal algebra. Results: The analysis supports the need for and benefit of bridging activities that make the connections to algebra explicit and for frequent reflection and consolidation tasks. Implications: Task and digital environment designers should consider designing bridging activities that consolidate, support and sustain students’ mathematical ways of thinking beyond their digital experience. Constructivist content: Our more general aim is to support the implementation of digital technologies, especially constructionist learning environments, in the mathematics classroom. (shrink)

Feldman has recently argued that leibniz never stated leibniz' law. This article seeks to rebut his arguments and makes a number of incidental points about the interpretation of the law.

Many biosystems are complex mixtures of disparate biofluids. To study contact and transport phenomena in these mixtures, one has to apply much information on the biofluids which are components of the mixtures. A lot of the corresponding data can be extracted by means of experiments. However, it is not always easy to obtain experimental results on rather deep physical characteristics of biofluids, especially if the bioparticles are complicated systems and the fluid coexists in the mixture with a large number of (...) other fluids. In these cases, the necessary data can, in principle, be extracted from those results which are easier to obtain experimentally. The present work proposes a method to evaluate the biofluid equilibrium pressure and electrochemical potential from common experimental values of the fluid concentration and absolute temperature as well as the fluid-particle mass, volume and spin. In so doing, the nonzero values of the particle volume are accounted for. The procedure is illustrated with a numerical example on the fluid of red blood cells (or erythrocytes) in human blood. The pressure values obtained are 49.1 and 38.8 micropascals for men and women respectively whereas the electrochemical-potential values are –2.124 and –2.130 electronvolts for men and women respectively. (shrink)

Following his retirement fromUniversity teaching in 1972 Bocheski focusedincreasingly on metaphilosophical issues. Someof these he considered in occasional papers,autobiographical essays, as well as interviews,often giving expression to views that are asrefreshing as they are – sometimes –surprising. Bocheski in his later years becamesomething of an iconoclast, sharply criticalof, indeed hostile to, much of what isparadigmatically taken to be `philosophy'. Inthis paper, I draw out and examine some aspectsof Bocheski's virtually anti-philosophicalattitudes and try my hand at an analysis ofwhat appears to (...) have become the Bocheski'smain underlying motivation in this respect: theless than happy interplay of religious faith,Weltanschauungen, and philosophy caughtbetween two seemingly persistent butconflicting inclinations of the human spirit tosubmit to the authority of some `total' picture. (shrink)

The characteristic sequence of hypergraphs Pn:n<ω associated to a formula φ, introduced in Malliaris [5], is defined by Pn=i≤nφ. We continue the study of characteristic sequences, showing that graph-theoretic techniques, notably Szemerédi’s celebrated regularity lemma, can be naturally applied to the study of model-theoretic complexity via the characteristic sequence. Specifically, we relate classification-theoretic properties of φ and of the Pn to density between components in Szemerédi-regular decompositions of graphs in the characteristic sequence. In addition, we use Szemerédi regularity to calibrate (...) model-theoretic notions of independence by describing the depth of independence of a constellation of sets and showing that certain failures of depth imply Shelah’s strong order property SOP3; this sheds light on the interplay of independence and order in unstable theories. (shrink)

This exploratory study contributes to the literature on disclosing concealable stigmatized identities (CSI) by positing authenticity and identity centrality as antecedents to disclosing body art within a workplace context. We analyze identity centrality and its effect on amplifying or suppressing disclosure and/or fear of disclosure of white‐collar professionals' body art. The research question focuses on whether white‐collar employees believe they can be authentic and disclose body art in the workplace and whether there are adverse career outcomes associated with disclosing body (...) art. Findings suggest authenticity was only related to the degree of disclosure through fear of disclosure, highlighting the role that fear played in the disclosure decision. Identity centrality moderated the relationship between authenticity and fear of disclosure. Both fear of and degree of disclosure were indirectly related to turnover intentions through affective organizational commitment. Given the limited research on body art as a stigma and its disclosure by white‐collar professionals, we believe this study adds to the CSI literature by offering insights into the impact that changing social mores associated with body art may have on the willingness of white‐collar professionals to disclose it. (shrink)

In this concluding reflection, the editors of this special issue reflect on the significance that Heidegger has had for French philosophy, precisely because of the creative and critical engagement of many of the original thinkers demonstrated above. It is not insignificant that Christian thinkers were drawn to Heidegger, seeing promise in his expansion of philosophical questioning, above all an enrichment of the idea of truth. However it is equally important to recognize that Heidegger’s native Christian roots were stripped of their (...) animating spirit, the question of God and the revelation of the Hebraic scriptures. It is thus notable that the criticisms from this conference originating from the side of faith frequently appeal to the Scriptures as they argue that there are truths which Heidegger himself simply does not seem to see. (shrink)